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Confocal immunofluorescence images of islets with insulin (green), and DAPI (blue) adapted from Banerjee et al. Diabetes 2016

tSNE of single-cell RNA sequencing of islets from nonpregnant and pregnant mice organized by cell type

THE BANERJEE LAB IS MOVING January 2026 to:
THE UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE IN TUCSON!


Our group works to expand the understanding of hormonal regulation of pancreatic islets in health and disease. A major focus of the lab is elucidating the normal physiologic adaptations of islets cells, particularly insulin-producing beta-cells, during pregnancy and the postpartum periods. We hope this knowledge will reveal how defective adaptations contributes to gestational diabetes (GDM) and the future risk of type 2 diabetes in women following pregnancy.  

More broadly, we anticipate that uncovering mechanisms of gestational beta-cell adaptation and their postpartum reversal will identify novel therapeutic targets to expand functional beta-cell mass and new treatments for of all types of diabetes.

University of Arizona

College of Medicine-Tucson

Updated December 2025

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